oxygenation effect of interventional lung assist in a lavage model of acute lung injury a prospective experimental study氧化的影响介入肺协助灌洗的急性肺损伤模型未来的实验研究.pdfVIP
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oxygenation effect of interventional lung assist in a lavage model of acute lung injury a prospective experimental study氧化的影响介入肺协助灌洗的急性肺损伤模型未来的实验研究
Available online /content/10/2/R56
Vol 10 No 2 Open Access
Research
Oxygenation effect of interventional lung assist in a lavage model
of acute lung injury: a prospective experimental study
Günther Zick, Inéz Frerichs, Dirk Schädler, Gunnar Schmitz, Sven Pulletz, Erol Cavus,
Felix Wachtler, Jens Scholz and Norbert Weiler
Department of Anesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, Germany
Corresponding author: Günther Zick, zick@anaesthesie.uni-kiel.de
Received: 20 Jan 2006 Revisions requested: 21 Feb 2006 Revisions received: 27 Feb 2006 Accepted: 13 Mar 2006 Published: 7 Apr 2006
Critical Care 2006, 10:R56 (doi:10.1186/cc4889)
This article is online at: /content/10/2/R56
© 2006 Zick et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction The aim of the study was to test the hypothesis repeated at different degrees of pulmonary gas exchange
that a pumpless arteriovenous extracorporeal membrane impairment with the pulmonary venous admixture ranging from
oxygenator (interventional lung assist (ILA)) does not 35.0% to 70.6%. The mean (± standard deviation) blood flow
significantly improve oxygenation in a lavage model of acute lung through ILA was 15.5 (± 3.9)% and 21.7 (± 4.9)% of cardiac
injury. output with one and both arteries open, respect
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