physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis生理功能、疾病活动和与健康有关的生活质量结果后3年adalimumab治疗强直性脊柱炎患者.pdf

Available online /content/11/4/R124 Vol 11 No 4 Open Access Research article Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis 1 2 3 4 Désirée M van der Heijde , Dennis A Revicki , Katherine L Gooch , Robert L Wong , 5 2 2 6 Hartmut Kupper , Neesha Harnam , Chris Thompson , Joachim Sieper for the ATLAS Study Group 1Department of Rheumatology, Leiden University Medical Center, Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands 2Center for Health Outcomes Research, United BioSource Corporation, 7101 Wisconsin Avenue, Suite 600, Bethesda, Maryland, 20814, USA 3Global Health Economics and Outcomes Research, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064, USA 4Formerly Abbott Immunology, Abbott Laboratories, 300 Interpace Parkway, Parsippany, New Jersey, 07054, USA 5Abbott GmbH Co. KG, Knollstrasse 50, Ludwigshafen, 67061, Germany 6Medical Department I, Rheumatology, Charité, Campus Benjamin Franklin, and German Rheumatism Research Center, Hindenburgdamm 30, Berlin, 12200, Germany Corresponding author: Désirée M van der Heijde, d.vanderheijde@kpnplanet.nl Received: 14 Apr 2009 Revisions requested: 5 Jun 2009 Revisions received: 16 Jul 2009 Accepted: 17 Aug 2009 Published: 17 Aug 2009 Arthritis Research Therapy 2009, 11:R124 (doi:10.1186/ar2790) This article is online at: /content/11/4/R124 © 2009 van der Heijde et al.; licensee BioMed Central Ltd. This is an open access article dist