predictors for good functional outcome after neurocritical care预测neurocritical护理后良好的功能结果.pdfVIP

Kiphuth et al. Critical Care 2010, 14:R136 /content/14/4/R136 RESEARCH Open Access Predictors for good functional outcome after neurocritical care 1* 1 1 1 2 2 Ines C Kiphuth , Peter D Schellinger , Martin Köhrmann , Jürgen Bardutzky , Hannes Lücking , Stephan Kloska , 1 1 Stefan Schwab , Hagen B Huttner Abstract Introduction: There are only limited data on the long-term outcome of patients receiving specialized neurocritical care. In this study we analyzed survival, long-term mortality and functional outcome after neurocritical care and determined predictors for good functional outcome. Methods: We retrospectively investigated 796 consecutive patients admitted to a non-surgical neurologic intensive care unit over a period of two years (2006 and 2007). Demographic and clinical parameters were analyzed. Depending on the diagnosis, we grouped patients according to their diseases (cerebral ischemia, intracranial hemorrhage (ICH), subarachnoid hemorrhage (SAH), meningitis/encephalitis, epilepsy, Guillain-Barré syndrome (GBS) and myasthenia gravis (MG), neurodegenerative diseases and encephalopathy, cerebral neoplasm and intoxication). Clinical parameters, mortality and functional outcome of all treated patients were analyzed. Functional outcome (using the modified Rankin Scale, mRS) one year after discharge was assessed by a mailed questionnaire or telephone interview. Outcome was dichotomized into good (mRS ≤ 2) and poor (mRS ≥ 3). Logistic regression analyses were calculated to determine independent predictors for good functional outcome. Results: Overall in-hospital mortality amounted to 22.5% of all patients, and a good long-term functional