prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome产前和围产期管理结果在巨大的胎盘和胎儿水肿chorioangioma复杂,胎儿贫血和孕产妇镜子综合症.pdfVIP

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prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome产前和围产期管理结果在巨大的胎盘和胎儿水肿chorioangioma复杂,胎儿贫血和孕产妇镜子综合症.pdf

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prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome产前和围产期管理结果在巨大的胎盘和胎儿水肿chorioangioma复杂,胎儿贫血和孕产妇镜子综合症

García-Díaz et al. BMC Pregnancy and Childbirth 2012, 12:72 /1471-2393/12/72 CASE REPORT Open Access Prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome 1 2 1 1,3,4* Lutgardo García-Díaz , Práxedes Carreto , Susana Costa-Pereira and Guillermo Antiñolo Abstract Background: Giant placental chorioangiomas have been associated with a number of severe fetal complications and high perinatal mortality. Case presentation: We report a case of giant chorioangioma with fetal hydrops, additionally complicated by severe anemia, mild cardiomegaly with hyperdinamic heart circulation and maternal mirror syndrome. Intrauterine blood transfusion and amniodrainage was performed at 29 weeks. Worsening of the fetal and maternal condition prompted us to proceed with delivery at 29 + 5 weeks. The newborn died 3 hours later due to pulmonary hypoplasia and hemodynamic failure. Maternal course was favourable, mirror syndrome resolved in the second day and the patient was discharged four days following delivery. Conclusions: In the case described here, fetal condition got worse despite of the anemia correction and amniodrainage. Our outcome raises the issue whether additional intrauterine clinical intervention, as intersticial laser, should have been performed to stop further deterioration of the fetal condition when progressive severe hydrops develops. Keywords: Fetal chorioangioma, Hydrops fetalis, Fetal anemia, Fetal therapy, Mirror syndrome Background high perinatal death rate (30–40%), a number of thera- Chorioangiomas are benign placenta