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Available online /content/10/4/R114 Vol 10 No 4 Open Access Research Reappraisal of Pseudomonas aeruginosa hospital-acquired pneumonia mortality in the era of metallo-β-lactamase-mediated multidrug resistance: a prospective observational study 1,2 2,3 4 Alexandre Prehn Zavascki , Afonso Luís Barth , Juliana Fernandez Fernandes , Ana Lúcia 1 3 2,4 Didonet Moro , Ana Lúcia Saraiva Gonçalves and Luciano Zubaran Goldani 1Infectious Diseases Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre – RS, Brazil 2Medical Sciences Postgraduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre – RS, Brazil 3Microbiology Unit, Clinical Pathology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre – RS, Brazil 4Division of Infectious Diseases, Hospital de Clínicas de Porto Alegre, Porto Alegre – RS, Brazil Corresponding author: Alexandre Prehn Zavascki, apzavascki@.br Received: 13 Apr 2006 Revisions requested: 22 May 2006 Revisions received: 3 Jun 2006 Accepted: 1 Aug 2006 Published: 1 Aug 2006 Critical Care 2006, 10:R114 (doi:10.1186/cc5006) This article is online at: /content/10/4/R114 © 2006 Zavascki et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction H