retrospective investigation of an influenza ah1n1pdm outbreak in an italian military ship cruising in the mediterranean sea, may-september 2009回顾性调查流感ah1n1pdm爆发在意大利军舰巡航在地中海may-september 2009.pdfVIP

Retrospective Investigation of an Influenza A/H1N1pdm Outbreak in an Italian Military Ship Cruising in the Mediterranean Sea, May-September 2009 1 2 2 3 4 Mario Tarabbo , Daniele Lapa , Concetta Castilletti , Pietro Tommaselli , Riccardo Guarducci , Giuditta ` 5 4 6 6 7 Luca , Alessandro Emanuele , Onofrio Zaccaria , Vincenzo F. P. La Gioia , Enrico Girardi , Maria R. Capobianchi2*, Giuseppe Ippolito7,8 1 Inspectorate of Health, ITA Navy, Rome, Italy, 2 Laboratory of Virology, National Institute for infectious Diseases ‘‘L. Spallanzani’’, Rome, Italy, 3 ITA Navy, Rome, 4 Military Hospital, ITA Navy, Taranto, Italy, 5 Frigate ‘‘Scirocco’’, ITA Navy, Italy, 6 Medical Situation Awareness Office, ITA Defence General Staff, Rome, Italy, 7 Department of Epidemiology, National Institute for Infectious Diseases ‘‘L. Spallanzani’’, Rome, Italy, 8 Scientific Direction, National Institute for Infectious Diseases ‘‘L. Spallanzani’’, Rome, Italy Abstract Background: Clinical surveillance may have underestimated the real extent of the spread of the new strain of influenza A/ H1N1, which surfaced in April 2009 originating the first influenza pandemic of the 21st century. Here we report a serological investigation on an influenza A/H1N1pdm outbreak in an Italian military ship while cruising in the Mediterranean Sea (May 24-September 6, 2009). Methods: The contemporary presence of HAI and CF antibodies was used to retrospectively estimate the extent of influenza A/H1N1pdm spread across the crew members (median age: 29 years). Findings: During the cruise, 2 crew members fulfilled the surveillance case definition for influenza, but onl