reproduction of overall spontaneous pain pattern by manual stimulation of active myofascial trigger points in fibromyalgia patients繁殖的自发性疼痛模式通过手动刺激活跃的纤维肌痛患者的肌筋膜触发点.pdfVIP

Ge et al. Arthritis Research Therapy 2011, 13:R48 /content/13/2/R48 RESEARCH ARTICLE Open Access Reproduction of overall spontaneous pain pattern by manual stimulation of active myofascial trigger points in fibromyalgia patients 1* 1 1,3 1 Hong-You Ge , Ying Wang , César Fernández-de-las-Peñas , Thomas Graven-Nielsen , Bente Danneskiold-Samsøe2, Lars Arendt-Nielsen1 Abstract Introduction: It has previously been reported that local and referred pain from active myofascial trigger points (MTPs) in the neck and shoulder region contribute to fibromyalgia (FM) pain and that the pain pattern induced from active MTPs can reproduce parts of the spontaneous clinical FM pain pattern. The current study investigated whether the overall spontaneous FM pain pattern can be reproduced by local and referred pain from active MTPs located in different muscles. Methods: A spontaneous pain pattern in FM was recorded in 30 FM patients and 30 healthy subjects served as controls. Local and referred pain patterns induced from active (patients) and latent (controls) MTPs were recorded following manual stimulation. The existence of MTPs was confirmed by intramuscular electromyographical registration of spontaneous electrical activity. Results: Local and referred pain areas induced from key active MTPs in FM were larger than pain areas from latent MTPs in healthy controls (P 0.001), but were similar to the overall spontaneous FM pain area in FM (P 0.05). The induced pain area was positively associated with current spontaneous pain intensity in FM (P 0.01). The locations of key active MTPs in FM patients were found to have latent MTPs in healthy subjects. The muscles containing key active MTPs in FM are often observed in