revealing the anti-tumor effect of artificial mirna p-27-5p on human breast carcinoma cell line t-47d揭示人工microrna的抗肿瘤效应对人类乳腺癌细胞系t-47d p-27-5p.pdfVIP

Int. J. Mol. Sci. 2012, 13, 6352-6369; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Revealing the Anti-Tumor Effect of Artificial miRNA p-27-5p on Human Breast Carcinoma Cell Line T-47D 1 2 3 1 Chien-Wei Tseng , Hsuan-Cheng Huang , Arthur Chun-Chieh Shih , Ya-Ya Chang , Chung-Cheng Hsu 1, Jen-Yun Chang 1, Wen-Hsiung Li 4,5,* and Hsueh-Fen Juan 1,* 1 Department of Life Science, Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan; E-Mails: angus8921@ (C.-W.T.); .tw (Y.-Y.C.); chung8421@.tw (C.-C.H.); jerris2004@ (J.-Y.C.) 2 Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Taiwan; E-Mail: hsuancheng@.tw 3 Institute of Information Science, Research Center for Information Technology Innovation, Academia Sinica, Taipei 115, Taiwan; E-Mail: arthur@.tw 4 Biodiversity Research Center and Genomics Research Center, Academia Sinica, Taipei 115, Taiwan 5 Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA * Authors to whom correspondence should be addressed; E-Mails: whli@ (W.-H.L.); yukijuan@.tw (H.-F.J.); Tel.: +1-773-702-3104 (W.-H.L.); +886-2(H.-F.J.); Fax: +1-773-702-9740 (W.-H.L.); +886-2(H.-F.J.). Received: 9 April 2