sarcocrassocolides m–o, bioactive cembranoids from the dongsha atoll soft coral sarcophyton crassocaulesarcocrassocolides m-o,生物活性cembranoids从东沙软珊瑚环礁sarcophyton crassocaule.pdfVIP

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sarcocrassocolides m–o, bioactive cembranoids from the dongsha atoll soft coral sarcophyton crassocaulesarcocrassocolides m-o,生物活性cembranoids从东沙软珊瑚环礁sarcophyton crassocaule.pdf

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sarcocrassocolides m–o, bioactive cembranoids from the dongsha atoll soft coral sarcophyton crassocaulesarcocrassocolides m-o,生物活性cembranoids从东沙软珊瑚环礁sarcophyton crassocaule

Mar. Drugs 2012, 10, 617-626; doi:10.3390/m OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Article Sarcocrassocolides M–O, Bioactive Cembranoids from the Dongsha Atoll Soft Coral Sarcophyton crassocaule Wan-Yu Lin 1, Yi Lu 1, Bo-Wei Chen 1, Chiung-Yao Huang 1, Jui-Hsin Su 2,3, Zhi-Hong Wen 1, Chang-Feng Dai 4, Yao-Haur Kuo 5 and Jyh-Horng Sheu 1,6,* 1 Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan; E-Mails: lemotylin@ (W.-Y.L.); snakefoot5052@ (Y.L.); a6152761@.tw (B.-W.C.); betty8575@.tw (C.-Y.H.); wzh@.tw (Z.-H.W.) 2 National Museum of Marine Biology Aquarium, Pingtung 944, Taiwan; E-Mail: x2219@.tw 3 Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan 4 Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan; E-Mail: corallab@.tw 5 National Research Institute of Chinese Medicine, Taipei 112, Taiwan; E-Mail: kuoyh@.tw 6 Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan * Author to whom correspondence should be addressed; E-Mail: sheu@.tw; Tel.: +886-7-5252000 (ext. 5030); Fax: +886-7-5255020. Received: 23 November 2011; in revised form: 29 February 2012 / Accepted: 29 February 2012 / Published: 8 March 2012 Abstract: Three new cembranoids, sarcocrassocolides M–O (1–3), have been isolated from the soft coral Sarcophyton crassocaule. The structures of the metabolites were determined by extensive spectroscopic analysis. Com