single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer单细胞测序分析特征共同muscle-invasive膀胱癌和cell-lineage-specific突变.pdfVIP
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single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer单细胞测序分析特征共同muscle-invasive膀胱癌和cell-lineage-specific突变
Li et al. GigaScience 2012, 1:12
/content/1/1/12
RESEARCH Open Access
Single-cell sequencing analysis characterizes
common and cell-lineage-specific mutations
in a muscle-invasive bladder cancer
1† 1† 1,2,3,4† 1,5,6† 7,8,9† 10 1
Yingrui Li , Xun Xu , Luting Song , Yong Hou , Zesong Li , Shirley Tsang , Fuqiang Li ,
11 1 1,12 1 1 1 1 1 1,5,6
Kate McGee Im , Kui Wu , Hanjie Wu , Xiaofei Ye , Guibo Li , Linlin Wang , Bo Zhang , Jie Liang , Wei Xie ,
Renhua Wu1 1 1 1 1 1 13 14 13
, Hui Jiang , Xiao Liu , Chang Yu , Hancheng Zheng , Min Jian , Liping Nie , Lei Wan , Min Shi ,
7,8,9 7,8,9 1 13 8,9,13 1 2
Xiaojuan Sun , Aifa Tang , Guangwu Guo , Yaoting Gui , Zhiming Cai , Jingxiang Li , Wen Wang ,
Zuhong Lu5,6 1 1,15 1,16 1 1*
, Xiuqing Zhang , Lars Bolund , Karsten Kristiansen , Jian Wang , Huanming Yang ,
Michael Dean11* and Jun Wang1,16,17*
Abstract
Background: Cancers arise through an evolutionary process in which cell populations are subjected to selection;
however, to date, the process of bladder cancer, which is one of the most common cancers in the world, remains
unknown at a single-cell level.
Results: We carried out si
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