slaughterhouse pigs are a major reservoir of streptococcus suis serotype 2 capable of causing human infection in southern vietnam屠宰场的猪链球菌血清型2的主要储层能够引起人类感染在越南南部.pdfVIP
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slaughterhouse pigs are a major reservoir of streptococcus suis serotype 2 capable of causing human infection in southern vietnam屠宰场的猪链球菌血清型2的主要储层能够引起人类感染在越南南部
Slaughterhouse Pigs Are a Major Reservoir of
Streptococcus suis Serotype 2 Capable of Causing
Human Infection in Southern Vietnam
1,4 1 1 2 1
Ngo Thi Hoa *, Tran Thi Bich Chieu , Tran Thi Thu Nga , Nguyen Van Dung , James Campbell , Pham
1 2 3 1,4 3
Hong Anh , Huynh Huu Tho , Nguyen Van Vinh Chau , Juliet E. Bryant , Tran Tinh Hien , Jeremy
Farrar1,4, Constance Schultsz1,5
1 Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 2 Sub-Department of Animal Health, Ho Chi Minh City, Vietnam,
3 Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 4 Centre for Tropical Medicine, Oxford University, Oxford, United Kingdom, 5 Academic Medical Centre, Centre
for Poverty-related Communicable Diseases, University of Amsterdam, Amsterdam, The Netherlands
Abstract
Streptococcus suis is a pathogen of major economic significance to the swine industry and is increasingly recognized as an
emerging zoonotic agent in Asia. In Vietnam, S. suis is the leading cause of bacterial meningitis in adult humans. Zoonotic
transmission is most frequently associated with serotype 2 strains and occupational exposure to pigs or consumption of
infected pork. To gain insight into the role of pigs for human consumption as a reservoir for zoonotic infection in southern
Vietnam, we determined the prevalence and diversity of S. suis carriage in healthy slaughterhouse pigs. Nasopharyngeal
tonsils were sampled from pigs at slaughterhouses serving six provinces in southern Vietnam and Ho Chi Minh City area
from September 2006 to November 2007. Samples were screened by b
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