steroid use in prowess severe sepsis patients treated with drotrecogin alfa (activated)使用类固醇在实力严重脓毒症患者drotrecogin阿尔法(激活).pdfVIP
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steroid use in prowess severe sepsis patients treated with drotrecogin alfa (activated)使用类固醇在实力严重脓毒症患者drotrecogin阿尔法(激活)
Available online /content/9/5/R502
Vol 9 No 5 Open Access
Research
Steroid use in PROWESS severe sepsis patients treated with
drotrecogin alfa (activated)
1 2 3 4
Howard Levy , Pierre-Francois Laterre , Becky Bates and Rebecca L Qualy
1Medical Director, Acute Care, Eli Lilly and Co., Indianapolis, Indiana, USA
2Professor in Medicine, Head of Intensive Care Medicine, Critical Care and Emergency Department, Cliniques Universitaires St Luc, UCL, Brussels,
Belgium
3Associate Senior Statistician, Eli Lilly and Co., Indianapolis, Indiana, USA
4Senior Scientific Communications Associate, Eli Lilly and Co., Indianapolis, Indiana, USA
Corresponding author: Howard Levy, hlevy@
Received: 2 May 2005 Revisions requested: 25 May 2005 Revisions received: 9 Jun 2005 Accepted: 1 Jul 2005 Published: 27 Jul 2005
Critical Care 2005, 9:R502-R507 (DOI 10.1186/cc3778)
This article is online at: /content/9/5/R502
© 2005 Levy et al.; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/
2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction In a study conducted by Annane, patients with organ dysfunctions, and were more commonly receiving
septic shock and unresponsive to adrenocorticotropic hormone mechanical ventilation. Among patients meeting AEC,
stimulation receiving low-dose steroid therapy had prolonged regardless of steroid treatment (n
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