steroidal and phenolic glycosides from the bulbs of lilium pumilum dc and their potential na+k+ atpase inhibitory activity甾类和酚苷灯泡的百合pumilum直流及其潜在na + k + atp酶抑制活性.pdfVIP
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steroidalandphenolicglycosidesfromthebulbsofliliumpumilumdcandtheirpotentialnakatpaseinhibitoryactivity甾类和酚苷灯泡的百合pumilum直流及其潜在nakatp酶抑制活性
Molecules 2012, 17, 10494-10502; doi:10.3390/molecules170910494
OPEN ACCESS
molecules
ISSN 1420-3049
/journal/molecules
Article
Steroidal and Phenolic Glycosides from the Bulbs of
+ +
Lilium pumilum DC and Their Potential Na /K ATPase
Inhibitory Activity
Zhong-Liu Zhou 1,*, Zong-Cai Feng 2, Chun-Yan Fu 3, Hua-Lin Zhang 1 and Jing-Min Xia 1
1 Chemistry Science and Technology School, Zhanjiang Normal University, 29 Cunjin Road,
Zhanjiang 524048, China; E-Mails: zhanghualing303@163.com (H.L.Z.);
xiajingming88@163.com (J.-M.X.)
2 Development Center for New Materials Engineering Technology in Universities of Guangdong,
Zhanjiang Normal University, 29 Cunjin Road, Zhanjiang 524048, China;
E-Mail: fengzongcai921@163.com
3 Department of Pharmacy, Shaoyang Medical College Level Speciaity School, 18 Baoqing Road,
Shaoyang 422000, China; E-Mail: chunyanfull@
* Author to whom correspondence should be addressed; E-Mail: zlzhou@;
Tel.: +86-137-2690-5138; Tel./Fax: +86-075-9318-3176.
Received: 2 July 2012; in revised form: 25 August 2012 / Accepted: 29 August 2012 /
Published: 3 September 2012
Abstract: A new steroidal saponin, named pumilum A (1), and a new phenolic glycoside,
threo-1-(4′-hydroxy-2′-methoxyphenyl)-2-(2′′,4′′-dihydroxyphenyl)-1,3-propanediol-4′-O-
β-D-glucopyranoside (7) were isolated from the methanolic extract of the bulbs of Lilium
pumilum DC, along with five known steroidal saponins. Their chemical structures were
elucidated on the basi
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