strong ion difference in urine new perspectives in acid-base assessment强离子不同尿液酸碱评价的新视角.pdfVIP

Available online /content/10/2/137 Commentary Strong ion difference in urine: new perspectives in acid–base assessment 1 2 2 2 Luciano Gattinoni , Eleonora Carlesso , Paolo Cadringher and Pietro Caironi 1Dipartimento di Anestesia, Rianimazione, e Terapia del Dolore, Fondazione IRCCS – ‘Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena’ di Milano, Istituto di Anestesiologia e Rianimazione, Università degli Studi di Milano, Milano, Italy 2Istituto di Anestesiologia e Rianimazione, Università degli Studi di Milano, Milano, Italy Corresponding author: Luciano Gattinoni, gattinon@policlinico.mi.it Published: 7 April 2006 Critical Care 2006, 10:137 (doi:10.1186/cc4890) This article is online at /content/10/2/137 © 2006 BioMed Central Ltd Abstract Please note that in the following discussion we will refer to The plasmatic strong ion difference (SID) is the difference between the amount of strong ion difference as SID (mEq), while we positively and negatively charged strong ions. At pH 7.4, temperature will refer to the strong ion difference concentration as [SID] 37°C and partial carbon dioxide tension 40 mmHg, the ideal value (mEq/l). of SID is 42 mEq/l. The buffer base is the sum of negatively – – – charged weak acids ([HCO ], [A ], [H PO ]) and its normal 3 2 4 By definition, strong ions are always dissociated in a solution. val