sudden death as presenting symptom caused by cardiac primary multicentric left ventricle rhabdomyoma, in an 11-month-old baby. an immunohistochemical study突然死亡症状引起的心脏原发性男性左心室横纹肌瘤,在一个11个月大的婴儿。.pdfVIP

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sudden death as presenting symptom caused by cardiac primary multicentric left ventricle rhabdomyoma, in an 11-month-old baby. an immunohistochemical study突然死亡症状引起的心脏原发性男性左心室横纹肌瘤,在一个11个月大的婴儿。.pdf

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sudden death as presenting symptom caused by cardiac primary multicentric left ventricle rhabdomyoma, in an 11-month-old baby. an immunohistochemical study突然死亡症状引起的心脏原发性男性左心室横纹肌瘤,在一个11个月大的婴儿。

Neri et al. Diagnostic Pathology 2012, 7:169 /content/7/1/169 CASE REPORT Open Access Sudden death as presenting symptom caused by cardiac primary multicentric left ventricle rhabdomyoma, in an 11-month-old baby. An immunohistochemical study 1 2 3 1 1 1 Margherita Neri , Sabina Di Donato , Rocco Maglietta , Cristoforo Pomara , Irene Riezzo , Emanuela Turillazzi and Vittorio Fineschi1* Abstract This case report describes a sudden cardiac death in an apparent healthy 11-month-old infant caused by a multifocal cardiac rhabdomyoma. Parents reported that a few days before the child had fallen to the ground getting a little superficial injury to the scalp. The authors hypothesize that it may have been a transient loss of consciousness episode caused by the cardiac tumour. After the gross examination, histological investigation supported by immunohistochemical analysis using antibody anti- Myoglobin, Actin, Vimentin, Desmin, CD34, S-100, Ki-67 was carried out for the diagnosis. Death was attributed to a multifocal cardiac rhabdomyoma, a benign tumour of striated muscle, which has been completely asymptomatic. In particular, one mass filled the entire posterior wall of the left ventricle. The insidious development of benign cardiac tumours also in infants and children is outlined, focusing on the responsible mechanisms of sudden death in such cases and providing a reference for additional study on these subjects. Virtual slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7163626988365078 Keywords: Cardiac rhabdomyoma, Sudden death, Cardiac tumours, Paediatric tumours Background con