原创力文档temperature changes among organophosphate poisoned patients, tehran- iran温度变化在有机磷中毒患者,德黑兰,伊朗.pdfVIP
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temperature changes among organophosphate poisoned patients, tehran- iran温度变化在有机磷中毒患者,德黑兰,伊朗
Talaie et al. DARU Journal of Pharmaceutical Sciences 2012, 20:52
/content/20/1/52
RESEARCH ARTICLE Open Access
Temperature changes among organophosphate
poisoned patients, Tehran- Iran
1,2 2 1,2 1 3,4*
Haleh Talaie , Hamid Owliaey , Abdolkarim Pajoumand , Mona Gholaminejad and Omid Mehrpour
Abstract
Background: Acute poisoning with organophosphorus compounds (OPs) is a major global clinical problem in the
developing countries. There have been many animal studies and few human surveys on the effects of
organophosphorus pesticide (OP) poisoning on thermoregulation. The aim of this prospective study was to
document the pattern of tympanic temperature changes among OP poisoned patients throughout the length of
their hospital stay.
Methods: 60 patients with diagnose of organophosphate poisoning were included in this study. Questioner was
filled out by trained nurses including demographic, clinical and paraclinical data. Tympanic temperature and Pulse
rate data of the cases were collected on five- occasions after admission.
Results: There were 41 (68.3%) male and 19 (31.7%) female, with a mean age of 34.4 ±19.4 years (range
13–89 years). Forty five patients had intentional poisoning for suicidal attempt. At the time of entry, the mean
tympanic temperature, pulse rate, respiratory rate and blood pressure (systolic and diastolic) of the OP poisoned
patients were respectively 37.1+/−0.6°C (36.0- 39.5), 91+/−18 (55– 145), 18+/−5.6 (8–44), 116+/−20 mm Hg (70– 170)
and 75+/−11.6 mm Hg (40– 110). 41.7% of the cases had serum butyryl cholinesterase activities (BChE) ≥ 50%
normal (≥1600 mU/ml). Our patients had normal temperature at the time entry (mean = 37.1). Tympanic
temper
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