testing limits to airflow perturbation device (apd) measurements测试限制气流扰动设备(adp)测量.pdfVIP

BioMedical Engineering OnLine BioMed Central Research Open Access Testing limits to airflow perturbation device (APD) measurements Erika R Lopresti*, Arthur T Johnson, Frank C Koh, William H Scott, Shaya Jamshidi and Nischom K Silverman Address: Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA Email: Erika R Lopresti* - erikalopresti@; Arthur T Johnson - artjohns@; Frank C Koh - kohf@; William H Scott - enduranc2@; Shaya Jamshidi - shaya.jamshidi@; Nischom K Silverman - nksilverman@ * Corresponding author Published: 31 October 2008 Received: 14 August 2007 Accepted: 31 October 2008 BioMedical Engineering OnLine 2008, 7:28 doi:10.1186/1475-925X-7-28 This article is available from: /content/7/1/28 © 2008 Lopresti et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The Airflow Perturbation Device (APD) is a lightweight, portable device that can be used to measure total respiratory resistance as well as inhalation and exhalation resistances. There is a need to determine limits to the accuracy of APD measurements for different conditions likely to occur: leaks around the mouthpiece, use of an oronasal mask, and the addition of resistance in the respiratory system. Also, there is a need for resistance measurements in patients who are ventil