the arabidopsis mei2 homologue aml1 binds atraptor1b, the plant homologue of a major regulator of eukaryotic cell growth的拟南芥mei2同系物aml1结合atraptor1b,植物同系物的真核细胞生长的主要监管机构.pdfVIP

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the arabidopsis mei2 homologue aml1 binds atraptor1b, the plant homologue of a major regulator of eukaryotic cell growth的拟南芥mei2同系物aml1结合atraptor1b,植物同系物的真核细胞生长的主要监管机构.pdf

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the arabidopsis mei2 homologue aml1 binds atraptor1b, the plant homologue of a major regulator of eukaryotic cell growth的拟南芥mei2同系物aml1结合atraptor1b,植物同系物的真核细胞生长的主要监管机构

BMC Plant Biology BioMed Central Research article Open Access The Arabidopsis Mei2 homologue AML1 binds AtRaptor1B, the plant homologue of a major regulator of eukaryotic cell growth Garrett H Anderson and Maureen R Hanson* Address: Molecular Biology and Genetics, Cornell University, Ithaca, NY 14850, USA Email: Garrett H Anderson - gha2@; Maureen R Hanson* - mrh5@ * Corresponding author Published: 21 February 2005 Received: 04 October 2004 Accepted: 21 February 2005 BMC Plant Biology 2005, 5:2 doi:10.1186/1471-2229-5-2 This article is available from: /1471-2229/5/2 © 2005 Anderson and Hanson; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: TOR, the target of the antibiotic rapamycin in both yeast and mammalian cells, is a potent cell growth regulator in all eukaryotes. It acts through the phosphorylation of downstream effectors that are recruited to it by the binding partner Raptor. In Arabidopsis, Raptor activity is essential for postembryonic growth. Though comparative studies suggest potential downstream effectors, no Raptor binding partners have been described in plants. Results: AtRaptor1B, a plant Raptor homologue, binds the AML1 (Arabidopsis Mei2-like 1) protein in a yeast two-hybrid assay. Thi