the basophil activation test by flow cytometry recent developments in clinical studies, standardization and emerging perspectives嗜碱细胞激活测试通过流式细胞术临床研究的最新进展,标准化和新兴的观点.pdfVIP
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the basophil activation test by flow cytometry recent developments in clinical studies, standardization and emerging perspectives嗜碱细胞激活测试通过流式细胞术临床研究的最新进展,标准化和新兴的观点
Clinical and Molecular Allergy BioMed Central
Review Open Access
The basophil activation test by flow cytometry: recent
developments in clinical studies, standardization and emerging
perspectives
1 1 1,2
Radhia Boumiza , Anne-Lise Debard and Guillaume Monneret*
Address: 1Immunology Laboratory, Lyon-Sud University Hospital, Lyon, France and 2Immunology Laboratory, Hôpital Neurologique, Lyon,
France
Email: Radhia Boumiza - radhiaboumiza@; Anne-Lise Debard - anne-lise.debard@chu-lyon.fr;
Guillaume Monneret* - guillaume.monneret@chu-lyon.fr
* Corresponding author
Published: 30 June 2005 Received: 04 May 2005
Accepted: 30 June 2005
Clinical and Molecular Allergy 2005, 3:9 doi:10.1186/1476-7961-3-9
This article is available from: /content/3/1/9
© 2005 Boumiza et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
allergybasophilsflow cytometryCD63CD203CCRTH2
Abstract
The diagnosis of immediate allergy is mainly based upon an evocative clinical history, positive skin
tests (gold standard) and, if available, detection of specific IgE. In some complicated cases, functional
in vitro tests are necessary. The general concept of those tests is to mimic in vitro the contact
between allerge
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