原创力文档the differences in brain activity between narrow band noise and pure tone tinnitus大脑活动之间的差异窄带噪声和纯质的音调耳鸣.pdfVIP
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the differences in brain activity between narrow band noise and pure tone tinnitus大脑活动之间的差异窄带噪声和纯质的音调耳鸣
The Differences in Brain Activity between Narrow Band
Noise and Pure Tone Tinnitus
1 1 1 2 1
Sven Vanneste *, Mark Plazier , Elsa van der Loo , Paul Van de Heyning , Dirk De Ridder
2 2
1 Brai n, Tinnitus Research Institute (TRI) and Department of Neurosurgery, University Hospital Antwerp, Edegem, Belgium, 2 Brai n, Tinnitus Research Institute (TRI) and
ENT, University Hospital Antwerp, Edegem, Belgium
Abstract
Background: Tinnitus is an auditory sensation characterized by the perception of sound or noise in the absence of any
external sound source. Based on neurobiological research, it is generally accepted that most forms of tinnitus are
attributable to maladaptive plasticity due to damage to auditory system. Changes have been observed in auditory
structures such as the inferior colliculus, the thalamus and the auditory cortex as well as in non-auditory brain areas.
However, the observed changes show great variability, hence lacking a conclusive picture. One of the reasons might be the
selection of inhomogeneous groups in data analysis.
Methodology: The aim of the present study was to delineate the differences between the neural networks involved in
narrow band noise and pure tone tinnitus conducting LORETA based source analysis of resting state EEG.
Conclusions: Results demonstrated that narrow band noise tinnitus patients differ from pure tone tinnitus patients in the
lateral frontopolar (BA 10), PCC and the parahippocampal area for delta, beta and gamma frequency bands, respectively.
The parahippoca
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