the dynamics of ebv shedding implicate a central role for epithelial cells in amplifying viral outputebv脱落的动力学影响上皮细胞的核心作用放大病毒输出.pdfVIP

The Dynamics of EBV Shedding Implicate a Central Role for Epithelial Cells in Amplifying Viral Output Vey Hadinoto., Michael Shapiro., Chia Chi Sun, David A. Thorley-Lawson* Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts, United States of America Abstract To develop more detailed models of EBV persistence we have studied the dynamics of virus shedding in healthy carriers. We demonstrate that EBV shedding into saliva is continuous and rapid such that the virus level is replaced in #2 minutes, the average time that a normal individ