原创力文档the effect of intra-abdominal hypertension incorporating severe acute pancreatitis in a porcine model腹腔的影响高血压合并急性胰腺炎在猪模型.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
the effect of intra-abdominal hypertension incorporating severe acute pancreatitis in a porcine model腹腔的影响高血压合并急性胰腺炎在猪模型
The Effect of Intra-Abdominal Hypertension
Incorporating Severe Acute Pancreatitis in a Porcine
Model
Lu Ke, Zhi-hui Tong, Hai-bin Ni, Wei-wei Ding, Jia-kui Sun, Wei-qin Li*, Ning Li, Jie-shou Li
Department of General Surgery, Jinling Hospital, Nanjing University, School of Medicine, Nanjing, China
Abstract
Introduction: Abdominal compartment syndrome (ACS) and intra abdominal hypertension(IAH) are common clinical
findings in patients with severe acute pancreatitis(SAP). It is thought that an increased intra abdominal pressure(IAP) is
associated with poor prognosis in SAP patients. But the detailed effect of IAH/ACS on different organ system is not clear.
The aim of this study was to assess the effect of SAP combined with IAH on hemodynamics, systemic oxygenation, and
organ damage in a 12 h lasting porcine model.
Measurements and Methods: Following baseline registrations, a total of 30 animals were divided into 5 groups (6 animals
in each group): SAP+IAP30 group, SAP+IAP20 group, SAP group, IAP30 group(sham-operated but without SAP) and sham-
operated group. We used a N2 pneumoperitoneum to induce different levels of IAH and retrograde intra-ductal infusion of
sodium taurocholate to induce SAP. The investigation period was 12 h. Hemodynamic parameters (CO, HR, MAP, CVP), urine
output, oxygenation parameters(e.g., S O , PO , PaCO ), peak inspiratory pressure, as well as serum parameters (e.g., ALT,
v 2 2 2
amylase, lactate, creatinine) were recorded. Histological examination of liver, intestine, pancreas, and lung was performed.
Main Results: Cardiac output significantly decreased in the SAP+IAH animals compared with other groups. Furthermore,
AST, creatinine, SUN and lactate showed similar increasing tendency paralleled with profoundly decrease
您可能关注的文档
- the c-terminal domains of nf-h and nf-m subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament networknf-h和nf-m c端域的子单元维护固定的轴突神经丝的内容通过阻断营业额神经丝网络.pdf
- the cues and care trial a randomized controlled trial of an intervention to reduce maternal anxiety and improve developmental outcomes in very low birthweight infants线索和护理实验干预的随机对照试验来降低孕产妇焦虑和提高极低出生体重婴儿的发育的结果.pdf
- the cuff-leak test what are we measuringcuff-leak测试我们测量.pdf
- the culprit behind amyloid beta peptide related neurotoxicity in alzheimer's disease oligomer size or conformation背后的罪魁祸首β淀粉样蛋白肽在阿尔茨海默病相关的神经毒性低聚物大小或构象.pdf
- the c-terminal tdp-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanismc端tdp-43片段聚合高倾向和显性负损害神经元的机制.pdf
- the cucl2al2o3 catalyst investigated in interaction with reagents与试剂cucl2al2o3催化剂进行交互.pdf
- the cumulative effects of polymorphisms in the dna mismatch repair genes and tobacco smoking in oesophageal cancer risk的累积影响dna错配修复基因的多态性和吸烟在食道癌的风险.pdf
- the curious case of arenavirus entry, and its inhibition好奇的沙粒病毒条目,及其抑制.pdf
- the current status of targeting baffblys for autoimmune diseases当前状态的目标baffblys自身免疫性疾病.pdf
- the curious connection between insects and dreams好奇的昆虫和梦想之间的联系.pdf
- the effect of monthly sulfadoxine-pyrimethamine, alone or with azithromycin, on pcr-diagnosed malaria at delivery a randomized controlled trial每月磺胺多辛-乙胺嘧啶的影响,单独或与阿奇霉素,pcr-diagnosed疟疾在交付一个随机对照试验.pdf
- the effect of osmolytes on protein fibrillationosmolytes在蛋白质纤维性颤动的影响.pdf
- the effect of oral sodium acetate administration on plasma acetate concentration and acid-base state in horses口服醋酸钠的影响政府在马等离子醋酸浓度和酸碱状态.pdf
- the effect of oxythioquinox exposure on normal human mammary epithelial cell gene expression a microarray analysis studyoxythioquinox暴露的影响在正常的人类乳腺上皮细胞基因表达微阵列分析研究.pdf
- the effect of marathon on mrna expression of anti-apoptotic and pro-apoptotic proteins and sirtuins family in male recreational long-distance runners马拉松的mrna表达抗凋亡的影响以及pro-apoptotic蛋白质和sirtuins蛋白家族男性休闲长跑.pdf
- the effect of polyterpenol thin film surfaces on bacterial viability and adhesionpolyterpenol薄膜表面细菌生存能力的影响和附着力.pdf
- the effect of postoperative hyperbaric oxygen treatment on intra-abdominal adhesions in rats术后高压氧治疗的效果在大鼠腹腔粘连.pdf
- the effect of predictability on subjective duration可预测性主观时间的影响.pdf
- the effect of raw soybean on oxidative status of digestive organs in mice生的影响大豆在小鼠消化器官的氧化状态.pdf
- the effect of pre-pregnancy body mass index and gestational weight gain on pregnancy outcomes in urban care settings in urmia-iran怀孕前体重指数的影响和妊娠期体重增加在urmia-iran妊娠结果在城市保健设置.pdf
文档评论（0）