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Adm. Sci. 2012, 2, 135-147; doi:10.3390/admsci2020135 OPEN ACCESS administrative sciences ISSN 2076-3387 /journal/admsci Commentary Urban Governance of Disease Rebecca Katz 1,*, Sangeeta Mookherji 1, Morgan Kaminski 1, Vibhuti Haté 2 and Julie E. Fischer 2 1 George Washington University, School of Public Health and Health Services, 2021 K Street, NW Suite 800, Washington, DC 20006, USA; E-Mails: smookher@ (S.M.); morgan.kaminski@ (M.K.) 2 Stimson Global Health Security Program, 1111 19th Street, NW, 12th Floor, Washington, DC 20036, USA; E-Mail: vhate@ (V.H.); jfischer@ (J.E.F.) * Author to whom correspondence should be addressed; E-Mail: rlkatz@. Received: 10 December 2011; in revised form: 19 March 2012 / Accepted: 26 March 2012 / Published: 5 April 2012 Abstract: Rapid population growth, urbanization, and the growing challenges faced by the urban poor require redefining the paradigm for public health interventions in the 21st century, creating new approaches that take urban determinants of health into consideration. The widening disparity between the urban poor and the urban rich further exacerbates health inequities. Existing tools for global governance of urban health risks fall short, particularly in the lack of formal mechanisms to strengthen collaboration and communication among national and municipal agencies and between th