zyxin links fat signaling to the hippo pathway河马通路zyxin链接脂肪信号.pdfVIP

Zyxin Links Fat Signaling to the Hippo Pathway Cordelia Rauskolb, Guohui Pan, B. V. V. G. Reddy, Hyangyee Oh, Kenneth D. Irvine* Howard Hughes Medical Institute, Waksman Institute, and Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of America Abstract The Hippo signaling pathway has a conserved role in growth control and is of fundamental importance during both normal development and oncogenesis. Despite rapid progress in recent years, key steps in the pathway remain poorly understood,