blocking of pdl-1 interaction enhances primary and secondary cd8 t cell response to herpes simplex virus-1 infection阻塞pdl-1交互提高中小学感染单纯疱疹virus-1 cd8 t细胞反应.pdfVIP

Blocking of PDL-1 Interaction Enhances Primary and Secondary CD8 T Cell Response to Herpes Simplex Virus- 1 Infection Rudragouda Channappanavar, Brandon S. Twardy, Susmit Suvas* Department of Biological Sciences, Oakland University, Rochester, Michigan, United States of America Abstract The blocking of programmed death ligand-1 (PDL-1) has been shown to enhance virus-specific CD8 T cell function during chronic viral infections. Though, how PDL-1 blocking at the time of priming affects the quality of CD8 T cell response to acute inf