conserved orb6 phosphorylation sites are essential for polarized cell growth in schizosaccharomyces pombe守恒orb6磷酸化网站对于极化在粟酒裂殖酵母细胞生长至关重要.pdfVIP
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conserved orb6 phosphorylation sites are essential for polarized cell growth in schizosaccharomyces pombe守恒orb6磷酸化网站对于极化在粟酒裂殖酵母细胞生长至关重要
Conserved Orb6 Phosphorylation Sites Are Essential for
Polarized Cell Growth in Schizosaccharomyces pombe
Guohong Liu, Dallan Young*
Departments of Biochemistry Molecular Biology and Oncology, University of Calgary, Calgary, Alberta, Canada
Abstract
The Ndr-related Orb6 kinase is a key regulator of polarized cell growth in fission yeast, however the mechanism of Orb6
activation is unclear. Activation of other Ndr kinases involves both autophosphorylation and phosphorylation by an
upstream kinase. Previous reports suggest that the
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