constructing biological pathways by a two-step counting approach构建生物通路的两步计算的方法.pdfVIP

Constructing Biological Pathways by a Two-Step Counting Approach Hsiuying Wang*, Henry Horng-Shing Lu, Tung-Hung Chueh Institute of Statistics, National Chiao Tung University, Hsinchu, Taiwan Abstract Networks are widely used in biology to represent the relationships between genes and gene functions. In Boolean biological models, it is mainly assumed that there are two states to represent a gene: on-state and off-state. It is typically assumed that the relationship between two genes can be characterized by two kinds of pairwis