constructing endophenotypes of complex diseases using non-negative matrix factorization and adjusted rand index构建复杂疾病的表型使用非负矩阵分解和调整兰德指数.pdfVIP

Constructing Endophenotypes of Complex Diseases Using Non-Negative Matrix Factorization and Adjusted Rand Index 1 2 2 2 2 Hui-Min Wang , Ching-Lin Hsiao , Ai-Ru Hsieh , Ying-Chao Lin , Cathy S. J. Fann * 1 Institute of Public Health, Yang-Ming University, Taipei, Taiwan, 2 Institute of BioMedical Science, Academia Sinica, Nankang, Taipei, Taiwan Abstract Complex diseases are typically caused by combinations of molecular disturbances