control growth factor release using a self-assembled [polycation∶heparin] complex使用自组装生长因子控制释放[聚阳离子∶肝素)复杂.pdfVIP

Control Growth Factor Release Using a Self-Assembled [polycation:heparin] Complex Blaine J. Zern¤a, Hunghao Chu¤b, Yadong Wang*¤b Wallace H. Coulter Department of Biomedical Engineering, School of Chemistry and Biochemistry, and Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America Abstract The importance of growth factors has been recognized for over five decades; however their utilization in medicine has yet to be fully realized. This is because free growth factors have short half-lives in plasma, maki