coordinated regulation of niche and stem cell precursors by hormonal signaling协调监管的利基和干细胞前体激素信号.pdfVIP

Coordinated Regulation of Niche and Stem Cell Precursors by Hormonal Signaling Dana Gancz, Tamar Lengil, Lilach Gilboa* Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel Abstract Stem cells and their niches constitute units that act cooperatively to achieve adult body homeostasis. How such units form and whether stem cell and niche precursors might be coordinated already during organogenesis are unknown. In fruit flies, primordial germ cells (PGCs), the precursors of germ line stem cells (GSCs), and somatic niche precursors develop