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- 2017-09-17 发布于上海
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detection and quantification of citrullinated chemokinescitrullinated趋化因子的检测和量化
Detection and Quantification of Citrullinated
Chemokines
Eva A. V. Moelants, Jo Van Damme, Paul Proost*
Laboratory of Molecular Immunology, Rega Institute, K.U. Leuven, Leuven, Belgium
Abstract
Background: Posttranslational deimination or citrullination by peptidylarginine deiminases (PAD) regulates the biological
function of proteins and may be involved in the development of autoimmune diseases such as rheumatoid arthritis and
multiple sclerosis. This posttranslational modification of arginine was recently discovered on inflammatory chemokines
in
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