direct interaction of endogenous kv channels with syntaxin enhances exocytosis by neuroendocrine cells直接相互作用的内源性kv通过神经内分泌细胞突触融合蛋白提高胞外分泌的频道.pdfVIP

Direct Interaction of Endogenous Kv Channels with Syntaxin Enhances Exocytosis by Neuroendocrine Cells Dafna Singer-Lahat, Dodo Chikvashvili, Ilana Lotan* Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel K+ efflux through voltage-gated K+ (Kv) channels can attenuate the release of neurotransmitters, neuropeptides and hormones by hyperpolarizing the membrane potential and attenuating Ca2+ influx. Notably, direct interaction between Kv2.1 channels overexpressed in PC12 cells and syntaxin has rece