dirichlet multinomial mixtures generative models for microbial metagenomics狄利克雷多项微生物宏基因组混合物生成模型.pdfVIP

Dirichlet Multinomial Mixtures: Generative Models for Microbial Metagenomics 1 2 2 Ian Holmes , Keith Harris , Christopher Quince * 1 Department of Bioengineering, University of California, Berkeley, California, United States of America, 2 School of Engineering, University of Glasgow, Glasgow, United Kingdom Abstract We introduce Dirichlet multinomial mixtures (DMM) for the probabilistic modelling of microbial metagenomics data. This data can be represented as a frequency matrix giving the