原创力文档distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of c3a receptor signaling in human mast cells独特的和共享的角色β-arrestin-1和β-arrestin-2 c3a的规定人类肥大细胞受体信号.pdfVIP
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distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of c3a receptor signaling in human mast cells独特的和共享的角色β-arrestin-1和β-arrestin-2 c3a的规定人类肥大细胞受体信号
Distinct and Shared Roles of b-Arrestin-1 and b-Arrestin-2
on the Regulation of C3a Receptor Signaling in Human
Mast Cells
Arpana Vibhuti., Kshitij Gupta., Hariharan Subramanian, Qiang Guo, Hydar Ali*
Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Abstract
Background: The complement component C3a induces degranulation in human mast cells via the activation of cell surface
G protein coupled receptors (GPCR; C3aR). For most GPCRs, agonist-induced receptor phos
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