distribution of extracellular glutamate in the neuropil of hippocampus海马细胞外谷氨酸的神经纤维网的分布.pdfVIP

Distribution of Extracellular Glutamate in the Neuropil of Hippocampus Melissa A. Herman.¤, Ben Nahir., Craig E. Jahr* Vollum Institute, Oregon Health and Science University, Portland, Oregon, United States of America Abstract Reported values of extracellular glutamate concentrations in the resting state depend on the method of measurement and vary ,1000-fold. As glutamate levels in the micromolar range can cause receptor desensitization and excitotoxicity, and thus affect neuronal excitability, an accurate determination of ambient glutamate is important