dynamic changes of the phosphoproteome in postmortem mouse brains在后期法动态变化的组织磷酸化蛋白质组老鼠的大脑.pdfVIP

Dynamic Changes of the Phosphoproteome in Postmortem Mouse Brains Tsutomu Oka., Kazuhiko Tagawa., Hikaru Ito, Hitoshi Okazawa* Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan Abstract Protein phosphorylation is deeply involved in the pathological mechanism of various neurodegenerative disorders. However, in human pathological samples, phosphorylation can be modified during preservation by postmortem factors such as time and temperature. Postmo