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- 2017-09-12 发布于上海
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eb1 is required for spindle symmetry in mammalian mitosis需要eb1主轴对称有丝分裂在哺乳动物
EB1 Is Required for Spindle Symmetry in Mammalian
Mitosis
¨
Anke Bruning-Richardson*, Kelly J. Langford, Peter Ruane, Tracy Lee, Jon M. Askham, Ewan E. Morrison
Leeds Institute of Molecular Medicine, University of Leeds, St. James’s University Hospital, Leeds, United Kingdom
Abstract
Most information about the roles of the adenomatous polyposis coli protein (APC) and its binding partner EB1 in mitotic
cells has come from siRNA studies. These suggest functions in chromosomal segregation and spindle positioning whose loss
might contribute to tumo
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