effects of altered maternal folic acid, vitamin b12 and docosahexaenoic acid on placental global dna methylation patterns in wistar rats的影响改变母体叶酸、维生素b12和二十二碳六烯酸在wistar鼠胎盘全球dna甲基化模式.pdfVIP

Effects of Altered Maternal Folic Acid, Vitamin B12 and Docosahexaenoic Acid on Placental Global DNA Methylation Patterns in Wistar Rats Asmita Kulkarni, Kamini Dangat, Anvita Kale, Pratiksha Sable, Preeti Chavan-Gautam, Sadhana Joshi* Department of Nutritional Medicine, Interactive Research School for Health Affairs, Bharati Vidyapeeth University, Pune, India Abstract Potential adverse effects of excess maternal folic acid supplementation on a vegetarian population deficient in vitamin B12 are poorly understood. We have previously shown in a rat model that