effects of solute-solute interactions on protein stability studied using various counterions and dendrimerssolute-solute交互作用对蛋白质稳定性的影响研究使用不同的抗衡离子和聚合物.pdfVIP

Effects of Solute-Solute Interactions on Protein Stability Studied Using Various Counterions and Dendrimers Curtiss P. Schneider., Diwakar Shukla.¤, Bernhardt L. Trout* Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America Abstract Much work has been performed on understanding the effects of additives on protein thermodynamics and degradation kinetics, in particular addressing the Hofmeister series and other broad empirical phenomena. Little attention, however, has