elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challenge海拔在发烧体温范围提高和延长后续反应的巨噬细胞内毒素挑战.pdfVIP

Elevation in Body Temperature to Fever Range Enhances and Prolongs Subsequent Responsiveness of Macrophages to Endotoxin Challenge Chen-Ting Lee, Lingwen Zhong, Thomas A. Mace, Elizabeth A. Repasky* Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York, United States of America Abstract Macrophages are often considered the sentries in innate immunity, sounding early immunological alarms, a function which speeds the response to infection. Compared to the large volume of studies on regulation of macrophage