【完整版】钛合金抗菌界面的构建本科毕业论文设计40论文41.doc

重庆大学本科学生毕业设计（论文） 钛合金抗菌界面的构建 学 生：何浩 学 号指导教师：刘鹏 专 业：生物工程 重庆大学生物医学工程联合学院 二O一五年六月 Graduation Design(Thesis) of Chongqing University construction of Titanium alloy antibacterial interface Undergraduate: HeHao Supervisor: Prof.LiuPeng Major: Bioengineering Bioengineering College of Chongqing University June 2015  摘 要 钛合金由于其良好的生物相容性和力学特性广泛用作骨科植入物。本文旨在改善的性能。本文具体包含如下研究内容：2）本表明：，的性，研究成果为在骨方面的应用提供了坚实的基础。  ABSTRACT Titanium and its alloy material due to its good biocompatibility and mechanical properties are widely used as orthopaedic implants. However, postoperative infection of titanium implant material of dye even lead to repeat the operation. Therefore, development with long-term antibacterial function of titanium implant material implant is of great significance to the clinical success. The purpose of this paper is to use layers of self-assembly technology in titanium coating on the surface building zinc ions in order to improve the antibacterial properties of titanium implant material.. The present work contains the following aspects: 1. Through layer upon layer on titanium alloy surface self-assembly technology for surface modification of titanium, with cationic polyethyleneimine as the first layer, and then press gelatinchitosanzinc ions is the order of the membrane, build antibacterial coating containing zinc ions.Antimicrobial coating surface morphology and elemental composition by scanning electron microscopy (sem) and EDS spectrum characterization. Determination results show that this experiment through layer upon layer self-assembly technology in titanium alloy surface and the success of the building containing zinc ions antibacterial coating. 2. In this thesis, staphylococcus aureus was used for untreated titanium and layers of self-assembly technology after processing of titanium antibacterial performance evaluation. Through the bacteriostatic circle experiment, antibacterial rat