原创力文档the interaction of dipole modifiers with polyene-sterol complexes偶极子之间的相互作用与polyene-sterol复合物修饰符.pdfVIP
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the interaction of dipole modifiers with polyene-sterol complexes偶极子之间的相互作用与polyene-sterol复合物修饰符
The Interaction of Dipole Modifiers with Polyene-Sterol
Complexes
Olga S. Ostroumova*, Svetlana S. Efimova, Evgeny G. Chulkov, Ludmila V. Schagina
Institute of Cytology of the Russian Academy of Sciences, St. Petersburg, Russia
Abstract
Recently, we showed that the effect of dipole modifiers (flavonoids and styrylpyridinium dyes) on the conductance of single
amphotericin B (AmB) channels in sterol-containing lipid bilayers primarily resulted from changes in the membrane dipole
potential. The present study examines the effect of dipole modifiers on the AmB multi-
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