the prognostic value of baseline erosions in undifferentiated arthritis基线的预后价值侵蚀在未分化的关节炎.pdfVIP

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the prognostic value of baseline erosions in undifferentiated arthritis基线的预后价值侵蚀在未分化的关节炎.pdf

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the prognostic value of baseline erosions in undifferentiated arthritis基线的预后价值侵蚀在未分化的关节炎

Available online /content/11/5/R155 Vol 11 No 5 Open Access Research article The prognostic value of baseline erosions in undifferentiated arthritis 1,2 1 1 Mohamed M Thabet , Thomas WJ Huizinga , Désirée M van der Heijde and Annette HM van der Helm-van Mil1 1Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, Leiden, PO Box 9600, 2300RC, The Netherlands 2Department of Internal Medicine, Assiut University Hospital, University Street 1, Assiut, P.O. Box 71515, Egypt Corresponding author: Mohamed M Thabet, m.thabet@lumc.nl Received: 5 Aug 2009 Revisions requested: 28 Aug 2009 Revisions received: 21 Sep 2009 Accepted: 15 Oct 2009 Published: 15 Oct 2009 Arthritis Research Therapy 2009, 11:R155 (doi:10.1186/ar2832) This article is online at: /content/11/5/R155 © 2009 Thabet et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Undifferentiated arthritis (UA) has a variable the absence of sustained remission during all available follow-up disease course; 40 to 50% of UA patients remit spontaneously, (mean 8 ± 3 years). while 30% develop rheumatoid arthritis (RA). Identifying the UA patients who will develop RA is essential to initiate early Results At baseline, 28.6% of UA patients had erosive joints. disease-modifying anti-rheumatic drug (DMARD) therapy. Presence of ≥2 erosive joints showed a positive predictive value Althoug