the relationship between the regional abdominal adipose tissue distribution and the serum uric acid levels in people with type 2 diabetes mellitus地区腹部脂肪组织分布之间的关系和血清尿酸水平在2型糖尿病患者.pdfVIP
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the relationship between the regional abdominal adipose tissue distribution and the serum uric acid levels in people with type 2 diabetes mellitus地区腹部脂肪组织分布之间的关系和血清尿酸水平在2型糖尿病患者
Kim et al. Diabetology Metabolic Syndrome 2012, 4:3
DIABETOLOGY
/content/4/1/3
METABOLIC SYNDROME
RESEARCH Open Access
The relationship between the regional abdominal
adipose tissue distribution and the serum uric
acid levels in people with type 2 diabetes
mellitus
Tae Ho Kim, Seong Su Lee, Ji Han Yoo, Sung Rae Kim, Soon Jib Yoo, Ho Cheol Song, Yong-Soo Kim, Euy Jin Choi
*
and Yong Kyun Kim
Abstract
Background: Hyperuricemia is associated with obesity. The visceral adiposity and subcutaneous adiposity may be
associated with the differential metabolic risk, and the distribution of abdominal adipose tissue was significantly
altered in people with type 2 diabetes mellitus (DM) compared to healthy people. Our study was performed to
determine to the association between the regional abdominal adipose tissue distribution and serum uric acid
levels in people with type 2 DM.
Methods: A total of 699 people with type 2 DM and who had undergone abdominal computed tomography
assessment of the visceral fat area and subcutaneous fat area were included. The serum uric acid levels were
measured by the uricase method. Hyperuricemia was defined by cut-off value of 7 mg/dl for men and 6 mg/
dl for women.
Results: The visceral fat area was positively associated with the serum uric acid levels after adjustment for age, sex,
systolic blood pressure, diastolic blood pressure, serum creatinine, hemoglobin, serum albumin, serum high-density
lipoprotein, serum triglyceride and hemoglobin A1c (b-coefficient = 0.117, p 0.001). The logistic regression
analysis showed that the visceral fat area was the sign
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