抗生素的不良反应（Adverse reactions of antibiotics）.doc

抗生素的不良反应（Adverse reactions of antibiotics） Adverse reactions of antibiotics [Abstract] objective to help clinicians understand the adverse drug reactions of antibiotics and promote rational use of antibiotics in clinic, so as to ensure the safety, effectiveness and rationality of the use of antibiotics. Methods: review of literature from allergic reaction and toxicity, specific reaction, double infection, drug combination cause or aggravate adverse reactions and other aspects, summarizes the antibiotic adverse drug reactions and clinical harm. Results the adverse reactions of antibiotics can be prevented and controlled, and the clinical monitoring should be paid attention to during the process of taking drugs. Conclusion the adverse drug reactions of antibiotics should be paid more attention to by clinicians. Key words] antibiotics; adverse reactions Adverse drug reactions are common in clinical medication. It refers not only to the side effects of drugs, but also to the toxicity, specific reactions, allergic reactions, secondary reactions, etc. [1]. Antimicrobial agents are the most commonly used drugs in clinic, including antibiotics, anti fungi, anti tuberculosis and antibacterial agents. Among them, there are the most varieties and quantities of antibiotics used in clinic. At present, there are more than 100 kinds of antibiotics commonly used in clinic. Antibiotics have saved countless lives, but their clinical use has also caused some adverse reactions [2]. The adverse clinical consequences of antibiotic adverse drug reactions are severe. After a few seconds to a few hours or even a long period of time after the drug withdrawal, adverse reactions can occur. Common allergic shock, fixed drug eruption, urticaria, vascular edema and other allergic reactions, gastrointestinal reactions, aplastic anemia, etc., and even cause death of patients (3). Therefore, to strengthen the supervision and rational use of antibiotics in the course of clinical medication is of grea