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0_7MPa氮氧混合气对大鼠脑电活动的影响
2000 9 21 3 Journal of Na y Medicine 2000 Sept. Vol. 21, No. 3 209
0. 7 M Pa *
毕 钢, 潘令松, 杨 涛, 肖 卫兵, 刘景昌
( 海军医学研究所, 上海 200433)
[ ] : 0. 7 MPa :
; , : 0. 7 MPa
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, : 0. 7 MPa , ,
, , N1 P1
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[ ] R845. 24 [ ] A [ ] 1009- 0754( 2000) 03- 0209- 03
Effects of 0. 7 MPa NitrogenOxygen Gas Mixture on
Electroencephalogram and Somatosensory Evoked Potential
BI Gang, PAN L ingsong, YAN G Tao, et al
(N aval Medical Research Institute, Shanghai 200433, China)
Abstract Objective T o obser e the pattern of effects 0. 7 MPa nitrogenoxygen gas mixture on electroencephalogram ( EEG)
and somatosensory e oked potential ( SEP) . Methods EEG was recorded by two needle electrodes punctured scalp with bipolar
electrode lead; SEP w as recorded w ith the same electrode lead as EEG, in addition, stimulatory electrode was punctured left rear leg.
Results Under 0. 7 MPa nitrogenoxygen gas mixture, there were no great changes in the beha ior of rats; the frequency of EEG w as
decreased, but amplitude of EEG w as not substant ially aried; P1 of SEP from stimulating left rear leg was not substantially aried,
but N 1 w as ob iously aried. The wa e of SEP was broad or tangent under high pressure. Conclusion rats w ere seized with mild
nitrogen narcosis when exposed to 0. 7 MPa nitrogenoxygen gas mixture. The ariation of EEG and SEP took place earlier than that
of beha ior. The frequency of EEG w as more sensiti e t han that of amplitude. N1 of SEP w as more sensit i e than P1 in nitrogen
narcosis.
Key words nitrogen narcosis; electroencephalogram; somatosensory e oked potential; nitrogenoxygen gas mixture
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, 10 min, ( 79% , 2 1% )
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