RGP镜片对儿童角膜敏感性影响.doc

RGP镜片对儿童角膜敏感性影响 　【摘要】 　　目的：研究儿童配戴RGP镜片后角膜敏感性的变化。方法：采用问卷的形式收集基本信息，应用Cochet and Bonnet aesthesiometer测量67例134眼角膜敏感性，按照不同分组进行比较分析。 结果：儿童戴镜1～12mo组，戴镜1～5a组中央部和下方角膜敏感性明显下降（中央P =0.000，下方P ＝0.002），而2组之间的差异无显著意义（中央P ＝0.997，下方P ＝0.056）。儿童戴镜1～5a组颞侧，鼻侧，上方角膜敏感性明显下降（颞侧P ＝0.000，鼻侧P ＝0.000，上方P ＝0.001），戴镜1～5a组与戴镜1～12mo组（颞侧P ＝0.133，鼻侧P ＝0.125,上方P ＝0.205），未戴镜组与戴镜1～12mo组（颞侧P ＝0.06，鼻侧P ＝0.200,上方P ＝0.207），差异均无显著意义。儿童与成年人分别配戴RGP镜片1～12mo和1～5a，中央角膜敏感性无显著差异（1～12mo P＝0.343，1～5a P ＝0.105）。结论：RGP镜片对于儿童和成人的中央角膜敏感性的影响是相似的。但由于儿童自身的特点，为儿童验配RGP仍应慎重。 【关键词】 RGP镜片　角膜敏感性(角膜知觉，CTT) 　　Effect of RGP contact lens on corneal sensitivity among children Abstract AIM: To evaluate corneal sensitivity variation of children after wearing RGP contact lens and to study the relationship between change of corneal sensation and wearing period.METHODS: A total of 67 subjects (134 eyes) were recruited. Questionnaire：age, types of contact lens, wearing periods, daily wearing time, disease associated with change of corneal sensitivity, complaint for wearing contact lens; Slit-lamp biomicroscopy examination: evaluate the fitting, examine cornea, conjunctiva; Corneal sensitivity measurement: measure corneal sensitivity at central, temporal, nasal, superior and inferior corneal location with Cochet and Bonnet aesthesiometer 10 minutes after removing contact lens. Analysis: The subjects were firstly divided into two groups: control group and experimental group. These two groups were further subgrouped on the basis of age, wearing period. The main statistic soft ware SPSS11.0 was used. RESULTS: Variation in corneal sensation of children after wearing RGP lens:(1)central and inferior location: corneal sensitivity significantly decreased within one year wear and one to five years wear（central P＝0.000，inferior P＝0.002）; No significant difference was between these two groups (central P ＝0.997，inferior P＝0.056). (2) nasal, temporal and superior: corneal sensitivity significantly decreased for one to five years wear（temporal P＝0.00