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肝癌介入治疗(Interventional therapy for liver cancer)
肝癌介入治疗(Interventional therapy for liver cancer)
Hepatocellular carcinoma, interventional radiology, treatment
Authors: Huang Xiaofei, Qi Yue, Hu Yan (medical imaging department, grade 01, class 96, Medical College of Hubei Three Gorges Medical College, Yichang 443003) Zhao Yun Li Hong (Medical Imaging Department) Wang Jiyao
Liver cancer accounts for third of the malignant tumors, and is a common disease in China and asia. More than 90% of HCC is primary hepatic carcinoma (PHC). The treatment is still the first choice for early detection and surgical resection, but the recurrence rate is higher, reaching 45.2% to 60%, and more than 70% of the cases have pulmonary metastasis [1]. In addition, early liver cancer has no clinical symptoms, most of which have been found in the middle and late stages, and lost the opportunity of operation. Interventional radiology developed in 70s is relatively safe, effective, minimally invasive and less painful. It is widely accepted as the first choice for the treatment of advanced liver cancer. The present status of interventional radiology treatment for liver cancer is summarized as follows. 1 theoretical basis for interventional radiology treatment of liver cancer
1.1 blood supply of liver and liver tumors
Research has confirmed that the normal liver tissue in portal vein and hepatic artery double blood supply, which accounted for 2/3 ~ 3/4 of portal vein blood, hepatic artery only 1/4 ~ 1/3; liver tumor blood supply and normal liver tissue compared with the changed, the blood supply from the hepatic artery in 90% and only 10% from the portal 2. Therefore, transcatheter arterial chemoembolization for hepatocellular carcinoma, the drug concentration within the tumor than peripheral vein administration is much higher, because the metabolism of liver, blood vessels around the drug concentration is not high, and the supply of nutrients embolism blocking vascular tumor and normal liver tissue blood supply has little effect on. As a result
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