深低温冷冻同种硬脑膜移植修复大面积关节软骨缺损(Repair of large articular cartilage defects with deep hypothermic homograft dura mater grafts).docVIP
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深低温冷冻同种硬脑膜移植修复大面积关节软骨缺损(Repair of large articular cartilage defects with deep hypothermic homograft dura mater grafts)
深低温冷冻同种硬脑膜移植修复大面积关节软骨缺损(Repair of large articular cartilage defects with deep hypothermic homograft dura mater grafts)
Repair of large articular cartilage defects with deep hypothermic homograft dura mater grafts
Update Date: 2010-08-04 Li Li Yuan Yuan
Articular cartilage defect is one of the important causes of joint dysfunction caused by various bone and joint diseases. Small cartilage defects can be repaired by autologous or allogeneic cartilage, cartilage membrane and periosteum. Repair of large articular cartilage defects is extremely difficult, therefore, according to the characteristics of morphology and organization principle and fetal cartilage regeneration of dural periosteum, foundation of success in animal studies 1 on the application of cryopreserved fetal dura graft to repair large area of articular cartilage defects.
clinical data
1. general data: this group is male 39, female 11, age 8~35 years old. The causes of extensive articular cartilage defects were suppurative arthritis (13 cases), rheumatoid arthritis (1 cases), osteoarthritis (10 cases), traumatic arthritis (5 cases), and exfoliative osteochondritis (4 cases). Among them, there were 43 cases of hip joint, 5 cases of knee joint and 2 cases of elbow joint.
2. fetal dural dissection and preservation: from 5 to 7 months the water bag abortion rivanol induced abortion or stillbirth in 1 hours with 1% chlorhexidine disinfection, asepsis from ear margin level will cut the fetal skull ring, remove the brain from the skull and scalp, the surface of the inner plate of a hat to the dura like the complete stripping can be applied immediately. Place the recipient in a sterile container and mark the date and place it in a -86 - depth freezer.
3. operation method: the elbow joint operation took the middle incision, the hip joint took the anterolateral incision, and the knee joint took the medial incision. The residual cartilage of the distal humerus, femoral head and femoral condyle was excised, and the sp
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