氯胺酮对心肌细胞内Mg2%2b浓度地调节机制地的研究.pdfVIP

遵义医学院硕+学位论文 英文摘要 wasnotaffectedintracellularCaH． [M92+]1 by 5．Inthe of extracellularNa+145mmol／L．theconcentration presence of[M92+] increasedat26．6％±5．8％in ventricular induced the myocytesb)’Ketamine．In presence ofextracellular Na+0 concentrationincreasedat mmol／L，the of[M92+]l 26．3％±7．6％in ventricular inducedKetamine．Statisticalresultsshowedthatnodifferenceswere myocytesby considered increase wasnotaffected significant(尸O．05)．Ketamine—induced of[M92+]1 extracellularNa+ by 6．In the ofextracellular Awereincubatedfor20min presence M92+，group by ketamineand Bcells wereincubatedfor20minwith10 SB202190before group Ltmol／L of ketamine．Theresultsshowedketamineinducedthe perfusion concentrationofthe intracellularflee ion was in magnesiumincreasingsignificantly group increase at69．89％±3．9％inB．Theresult that of[M92]J ketamineinduced group suggest theconcentration oftheintracellularfree ion was magnesium increasingsignificantly blocked bytheMAPKinhibitor-SB202190．Statisticalresultsshoweddifferenceswere cons